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Bioastronautics Symposium: Genomics in Space

With Dr. Michael Schmidt | Dr. Christopher Mason | Chris Bradburne |

Event Detailsexpand

Presented by the JHU Human Spaceflight Lab (bioastronautics@hopkins), the Whiting School of Engineering Office of Research and Translation, and Hopkins at Home

Click here to register and join the livestream on June 11th

In the near future, government spaceflights will become more ambitious, with the NASA Artemis program sending people back to the moon (and later missions going on to Mars). At the same time, commercial spaceflight providers (SpaceX, Axiom, Blue Origin) are sending people into space who might not have the same levels of health and fitness as government astronauts. Both of these circumstances will challenge the ability of humans to tolerate spaceflight and perform inflight tasks in an extreme environment. Among the approaches to address this issue is genomic analysis: assessing a given person’s genetic predisposition to tolerate the stressors of spaceflight, measuring changes in genetic (epigenetic) makeup as a consequence of spaceflight, and developing countermeasures to the effects of spaceflight based on these individualized and personalized responses. The speakers in this symposium are experts in this field and are at the forefront of research into spaceflight effects on the genome.

Disclaimer: The perspectives and opinions expressed by the speaker(s) during this program are those of the speaker(s) and not, necessarily, those of Johns Hopkins University and the scheduling of any speaker at an alumni event or program does not constitute the University’s endorsement of the speaker’s perspectives and opinions.
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About Dr. Michael Schmidtexpand


Dr. Michael Schmidt

Dr. Michael A. Schmidt is among those leading the advancement of precision medicine in human spaceflight.  His clinical and research work is focused on multi-omics analysis, including the NASA Twins Study of One Year in Space, Inspiration4, Polaris Dawn, Axiom-1, Axiom-2, Axiom-3, and other civilian missions.  His work in functional genomics and functionally characterized molecular networks has been central to his team’s development of the Astronaut Digital Twin (ADT) platform for human spaceflight. Dr. Schmidt’s clinical work in genomics stresses the need to understand gene signatures within the broader context of molecular networks, including transcripts, proteins, metabolites, and others. He has also developed a working pharmacogenomics methodology to personalize drug prescribing for astronauts.Dr. Schmidt is the CEO and Chief Scientific Officer of Sovaris Aerospace.Dr. Schmidt is the former President of the Life Sciences and Biomedical Engineering Branch of the Aerospace Medical Association (currently on the Board of Governors) and is a founding member of the Precision Medicine & Pharmacometabolomics Task Group of the Metabolomics Society.  Dr. Schmidt did his Ph.D. research in Molecular Medicine & Biochemistry at NASA Ames Research Center and did a second Ph.D. in Neuroscience at Lancaster University (UK), with additional studies in data and models at MIT.

About Dr. Christopher Masonexpand


Dr. Christopher Mason

Christopher Mason, PhD is a Professor of Genomics, Physiology, Biophysics, and Neuroscience at Weill Cornell Medicine and Director of the WorldQuant Initiative for Quantitative Prediction. He completed a dual B.S. in Genetics & Biochemistry at University of Wisconsin-Madison (2001), a Ph.D. in Genetics at Yale University (2006), Clinical Genetics Fellowship at Yale Medical School (2009), and was the Visiting Fellow of Genomics, Ethics, and Law at Yale Law School (2006-2009). His laboratory creates and deploys new technologies and algorithms for medicine, integrative omics, and cell/genome engineering, spanning more than 350 peer-reviewed papers, five patents, five diagnostics tests, ten biotechnology companies, and four non-profits. Dr. Mason also holds affiliate faculty appointments at the New York Genome Center, Yale Law School, and the Consortium for Space Genetics at Harvard Medical School. He is the author of The Next 500 Years: Engineering Life to Reach New Worlds and The Age of Prediction.

About Chris Bradburneexpand


Chris Bradburne

Chris Bradburne is a Section Supervisor for Sequencing and Computational Biology at the Johns Hopkins University Applied Physics Laboratory, and an Associate Professor in the Johns Hopkins Department of Genetic Medicine. His work includes helping establish standards and methods for bacterial and viral sampling, sequencing, and targeted enrichment, and employing genomic surveillance to inform risks for Coronavirus emergence from environmental reservoirs in Bangladesh and Ghana.  He also leads efforts to establish human adverse outcomes pathways to enable cell-culture testable, explainable pathways for infectious disease susceptibility, as well as employing systems biology models for n-of-1 precision medicine and animal One Health applications.